In order to give you better service we use cookies. By continuing to browse the site you are agreeing to our use of cookies.
Breast Stained with Estrogen Receptor antibody

Estrogen Receptor (1D5) 0,1 ml

Estrogen Receptor (1D5) 1,0ml
Specificity and Comments:
The estrogen receptor (ER) is a 66-kDa protein that mediates the actions of estrogens in estrogen-responsive tissues. It is a member of a large superfamily of nuclear-hormone receptors that function as ligand-activated transcription factors. The ER gene consists of more than 140kb of genomic DNA divided into 8 exons. These translate into a protein with six functionally discrete domains, labeled A through F. A second form of the estrogen receptor, ER? has recently been described. ER [clone 1D5] reacts with the amino-terminal domain in the A/B region of ER?. This clone has been established to work in formalin-fixed, paraffin-embedded tissues and has been published in numerous breast cancer research studies. Staining patterns observed include: ER+ and PR+, ER+ and PR-, ER- and PR+, and ER- and PR-.
(Key Reference: Pertschuk)
Species Reactivity:
Human and rat; others not tested.
Clone: 1D5
Isotype: IgG1/?
Human recombinant estrogen-receptor protein
Known Applications: Immunohistochemistry (frozens/formalin–fixed paraffin-\ embedded tissues).
FDA Ruling: Class 1
Positive Control: Breast carcinoma
Cellular Localization: Nuclear
Supplied As:
Buffer with protein carrier and preservative
Storage and Stability:
Store vial at 4°C. Stable for 18 months.
Start > Finland E-line > Immunohistokemia > Vasta-aineet D-F > Estrogen Receptor (1D5) 0,1 ml