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Squamous cell carcinoma in lung stained with EGFR

Epidermal Growth Factor Receptor (EGFR) 1,0 mL

BC-CM063CK
Description
Epidermal Growth Factor Receptor (EGFR) 1,0 mL
Specificity and Comments:
EGFR recognizes a 170kDa protein, identified as the first member (EGR-Receptor) of type I family of growth factor receptors. It shows no cross-reaction with c-erbB-2, cerbB-3 or c-erbB-4. Over-expression of EGFR is reported in tumors of breast (25%), brain, bladder, lung, gastric, esophagus, cervix, ovary and endometrium.
Species Reactivity: Human
Clone: 111.6
Isotype: IgG1
Immunogen:
Extracellular domain of human recombinant EGFR
Known Applications: Immunohistochemistry (formalin–fixed paraffin embedded tissues)
Positive Control:
Squamous cell carcinoma or colon cancer
Cellular Localization:
Cell membrane and some cytoplasmic
Supplied As:
1. Buffer with protein carrier and preservative
2. 1.5 ml conc. Pronase (Cat # PRT957Q)
3. 6.0 ml of Pronase Buffer (Cat # PRB957G)
Storage and Stability:
Store vial at 4°C. Product is 18 months.
Start > Finland E-line > Immunohistokemia > Vasta-aineet D-F > Epidermal Growth Factor Receptor (EGFR) 1,0 mL
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